Axel Künstner graduated in Computer Sciences and received his PhD at the Uppsala University (Sweden) working with Hans Ellegren. During this time his research was focused on genomics and transcriptomics in birds. Afterwards, he moved to the Max-Planck-Institute for Developmental Biology in Tübingen to work on the guppy genome project where he combined population genetic approaches and whole genome sequencing to investigate selection due to natural barriers in guppies.

In autumn 2014, he became a member at the Lübeck Institute for Experimental Dermatology and is working in close collaboration with the Max-Planck-Institute for Evolutionary Biology in Plön. His main focus was to analyse microbiome data. Among others, he participates in projects investigating differences in skin microbiota in bullous pemphigoid patients compared to healthy controls.

Currently, he is part of the Group for Medical Systems Biology lead by Prof. Hauke Busch.